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Acta obstetricia et gynecologica Scandinavica.2025 4

women planning pregnancy should stop GLP-1 medications at least 2 months before attempting to conceive

These biological processes are closely associated with connective tissue function and structural recovery in laboratory models

It reduces type 2 diabetes risk, enhances insulin sensitivity, and aids weight loss

Combining the two could theoretically worsen these symptoms, though this has not been formally studied

4 Discussion Based on current RCT evidence, our meta-analysis showed that semaglutide significantly reduces MACE risk in patients with T2DM, primarily by lowering nonfatal myocardial infarction risk, with no significant effects on cardiovascular death or nonfatal stroke