Health benefits and anti-inflammatory activities have been attributed to the activity of tocochromanol catabolites, especially the 13'-COOH catabolite since it inhibits 5-lipoxygenase a key enzyme in the biosynthesis of leukotrienes from arachidonic acid
Headache or dizziness Rapid changes in blood pressure, hydration, or electrolyte balance during intravenous injections can cause mild headaches or lightheadedness
Medically reviewed by Charles Kamen, MD, board-certified neurologist Initial medical evaluation is $88
10.1007/s00268-012-1663-4 146 VukojevicJ.SiroglavicM.KasnikK.KraljT.StancicD.KokotA.et al (2018)
Here's what you should consider to make sure you are getting the potency you expect from your supplement
The peptide increases expression of TLE1 (an NF-B inhibitor) by 762% and IL18BP (another NF-B inhibitor) by 295%, potentially inhibiting inflammatory NF-B protein activity despite increasing NF-B2 expression by 103%