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Intention-to-treat analyses (mean follow-up: 970 days for SGLT-2i users and 992 days for GLP-1RA users) resulted in an HR of 1.36 (95% CI 0.51, 3.61)

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4 Importantly, several biological abnormalities, including inflammatory markers and brain metabolic changes, may fluctuate across mood states, whereas others (e.g., mitochondrial dysfunction) may represent more stable trait-like features

This individualized approach also helps establish realistic expectations

I feel this fear is unfounded, doctors in countries who do allow OTC still prescribe and administer B12 injections to patients who need them