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These areas remain the focus of laboratory and preclinical research aimed at advancing scientific understanding of peptide biology, cellular signaling, and molecular pharmacology
Berberine Berberine is one of the most studied natural compounds for metabolic health
The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance
Faster Recovery: Speeds up recovery after workouts, injury, or surgery by improving tissue regeneration
Beyond its interaction with lipid enzymes, our MS interactome analysis also indicates that the GLP-1R binds to ERMCS-localised Sarcoendoplasmic Reticulum Calcium ATPase (SERCA) pump 88 in the ER and voltage-dependent anion-selective channel protein 2 (VDAC2) in the OMM, both involved in calcium/ion transfer across ERMCSs 89 , suggesting a prominent role for the receptor in the control of intra-organelle ion homeostasis, with important implications for the regulation of mitochondrial function, ER stress responses and insulin secretion 90
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