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There are several potential reasons for the reduced magnitude of effects on primary endpoints related to cognitive decline
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When to Consider Testing Testing may be useful: Before starting a GLP-1 medicine After a meaningful treatment change When diabetes goals are not being met When persistent gastrointestinal symptoms develop When food or fluid intake has significantly decreased When kidney or liver risk is already present When a prior result was abnormal When a healthcare provider recommends follow-up Testing frequency should be based on individual risk rather than an automatic monthly or quarterly panel for everyone
Table 1 Animal studies evaluating the anti-inflammatory effect of GLP-1 in atherosclerosis
Students might think semaglutide is directly extracted from lizard venom
PMID: 34751700
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