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The challenge with ankle healing relates partly to the structures involved

BPC-157 is widely used in the regenerative medicine community and the healing effects among the human guinea pigs are predominantly positive, but safety is a big unknown

For comparison, vitamin C increased collagen in 50% of subjects, and retinoic acid (prescription-strength retinoid) increased collagen in only 40%

AOD 9604 is considered safe when administered under medical supervision, with a favorable safety profile compared to full HGH treatments

Some have plausible mechanisms and early evidence

The research here is mechanistically plausible but not directly studied for BPC-157 specifically