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Possible Side Effects While generally well-tolerated, some individuals may experience mild side effects such as: Pain, redness, or swelling at the injection site Mild diarrhea or stomach upset Allergic reactions like rash, itching, or dizziness in rare cases Headache or flushing due to niacinamide content Any persistent or severe symptoms should be reported to a healthcare professional promptly

It carries the strongest evidence base because most published protocols describe this exact schedule

The mechanism involves upregulation of matrix metalloproteinases (MMPs) and their inhibitors, which remodel collagen in a more organized way than unassisted healing

Because they act through non-overlapping mechanisms, some protocols examine them in combination or parallel though combination research should have a clear mechanistic rationale

But dose reduction is a legitimate strategy in several situations

Side effects include nausea if overdosed and an unnatural orange-tinted tanning effect