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However, a retrospective cohort study published in Diabetes Care did find that use of GLP-1 medications for 1-3 years was associated with a slightly increased risk of all thyroid cancer (adjusted hazard ratio 1.58) and medullary thyroid cancer specifically (adjusted hazard ratio 1.78)

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This large muscle is easily identified on the upper, outer thigh making it a safe injection site for self-administration

For gastrointestinal applications, digestive comfort may improve within the first 1 to 2 weeks, progressing to sustained improvements in food tolerances by weeks 5 to 6

Patients experiencing severe or persistent vomiting or diarrhea should be monitored for dehydration and potential acute kidney injury

If a patient is NPO (nothing by mouth) for any reason, the gastric emptying delay becomes irrelevant, and the practical question shifts to whether the GLP-1 should be continued during hospitalization