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The trade-off is extra complexity
document solvent, concentration, and prep date Minimize moisture and airborne contamination during weighing Follow institutional SOPs and appropriate containment Restrictions Laboratory research use only No clinical or veterinary applications No therapeutic or diagnostic claims Technical Specifications Storage & Notes Record lot, solvent system, concentration, and preparation date
For severe deficiency, patients get 1,000 mcg daily for the first week
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More substantial improvements, if they occur, generally become apparent between months four and six
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